Fieggen G, Fieggen K, Stewart C, Padayachy L, Lazarus J, Donald K, Dix-Peek S, Toefy Z, Figaji A. (2014) Spina bifida: a multidisciplinary perspective on a many-faceted condition. South African Medical Journal. 2014 Mar;104(3):213-7.
Open spina bifida
or myelomeningocele (SBM) is the most common birth defect involving the
central nervous system, second only in incidence to congenital cardiac
disease. Outcomes in this disorder were poor until the mid-20th century,
when modern neurosurgical techniques (closing the lesion and treating
hydrocephalus) and treatment for the neuropathic bladder addressed the
major causes of mortality, although SBM may still be poorly treated in
the developing world. Initial management - or mismanagement - has a
profound impact on survival and long-term quality of life.
- PMID: 24897828
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