Game X, Villers A, Malavaud B, Sarramon J. (1999) Bladder cancer arising in a spina bifida patient.
Urology. 1999 Nov;54(5):923.
We report the case of a 52-year-old patient with spina bifida,
neurologic bladder, and a history of recurrent urinary tract infections
(UTIs) in whom a bladder cancer was incidentally discovered. Cytology,
cystoscopy, and cystography showed nonspecific, extensive inflammatory
lesions. Cystography demonstrated a complex of diverticulae and
cellules. Pathologic examination of a diverticulectomy specimen revealed
a grade III pT3b transitional and squamous cell carcinoma. Because of
the similar disease causation (recurrent UTIs, stones, and indwelling
catheterization), we suggest extension of the guidelines proposed for
patients with spinal cord injuries (ie, annual serial bladder biopsies)
to patients with nontraumatic neurogenic bladder.
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