Ebid AA, Abd El-Kafy EM, Alayat MS. (2013) Effect of Pulsed Nd:YAG Laser in the Treatment of Neuropathic Foot Ulcers in Children with Spina Bifida: A Randomized Controlled Study. 
Photomedicine and Laser Surgery. 2013 Oct 25. 
Abstract
Abstract Objective:
 This study assessed the effects of pulsed Nd:YAG laser treatment of 
neuropathic foot ulcers in children with spina bifida. Background data: Children with spina bifida
 face increased risk for developing neuropathic foot ulcers. Methods: In
 a randomized controlled trial, 39 children and adolescents (ages 6-15 
years) with spina bifida
 and stage III neuropathic foot ulcers were randomly assigned to the 
laser group or the placebo laser group. The former received pulsed 
Nd:YAG laser treatments (i.e., total energy of 300-350 J during three 
sessions/week) plus standard wound care, and the latter received sham 
laser treatments plus standard wound care. Wound size and wound 
appearance were assessed for all patients at the beginning of the 
treatment, after 5 weeks, and after 10 weeks. Results: The decrease in 
wound surface area at 5 and 10 weeks post- treatment was significantly 
greater in the laser group (i.e., 2.44±0.33 and 0.29±0.25 cm2, respectively) than in the placebo group (i.e., 3.81±0.18 and 3.24±0.44 cm2,
 respectively). Also, the decrease in the total score for the Pressure 
Sore Status Tool (PSST) at 5 and 10 weeks post-treatment was 
significantly different for the laser group (i.e., 32.76±2.30 and 
17.52±1.66, respectively) than for the placebo group (i.e., 46.50±2.12 
and 38.11±3.17, respectively). Conclusions: Treatment with pulsed 
neodymium:yttrium aluminum garnet (Nd:YAG) laser combined with standard 
wound care decreases wound size and improves wound appearance for stage 
III neuropathic foot ulcers in children with spina bifida.
- PMID: 24160904
 
 
 
 
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