Comparison of prenatal and postnatal treatments of spina bifida in Poland - a randomized, single-center study

Zamłyński J, Olejek A, Bohosiewicz J, Koszutski T, Ziomek G, Horzelska E, Gajewska-Kucharek A, Maruniak-Chudek I, Herman-Sucharska I, Kluczewska E, Horak S, Bodzek P, Zamłyński M, Kowalik J, Horzelski T. (2013).  Comparison of prenatal and postnatal treatments of spina bifida in Poland - a randomized, single-center study.

Journal of Maternal-Fetal and Neonatal Medicine. 2013 Oct 25. [Epub ahead of print]

Abstract

Abstract Objective: The aim of the study was a randomized comparison of the outcomes of intrauterine myelomeningocele repairs (IUMR) in type II Chiari malformation (II CM) fetuses with clinical data of newborns and infants operated on postnatally. Methods: The study group (SG) comprised of 46 pregnant women whose type II CM children underwent IUMR, while 47 pregnant women whose type II CM children were operated on postnatally constituted the control group (CG). A total of 24 SG and 20 CG patients reached the endpoint of the study. Results: High incidence of PROM (24 (52.2%), CI 3.74 (1.69-8.26) (p<0 .001="" 0.35="" 1.86="" 16="" able="" adaptive="" adverse="" after="" and="" are="" as="" can="" cg="" chiari="" children="" ci="" closure="" compared="" conclusions:="" contrast="" controls.="" controls="" course="" equipment.="" especially="" evolution="" for="" from="" further="" group="" ii="" implantation="" in="" independently.="" ipprom="" iumr.="" iumr="" labor="" lower="" lowers="" malformation.="" measures="" mmc="" need="" needed="" none="" noted="" of="" on="" p="" postnatally="" postoperative="" prenatal="" preterm="" preventive="" respectively="" shunt="" significantly="" statistically="" studies="" study="" surgeries="" the="" to="" treated="" two="" type="" vp="" walk="" was="" without="">

 

PMID:24156622